Probing the physical hallmarks of cancer.
Nat Methods. 2025;:ePub - PMID: 39815103 - DOI: 10.1038/s41592-024-02564-4
Targeting EPHB2/ABL1 restores antitumor immunity in preclinical models of ependymoma.
Proc Natl Acad Sci U S A. 2025;122(4):e2319474122 - PMID: 39841145 - PMCID: PMC11789170 - DOI: 10.1073/pnas.2319474122
Spatial-temporal heterogeneities of liver cancer and the discovery of the invasive zone.
Using mathematical modelling and AI to improve delivery and efficacy of therapies in cancer.
Nat Rev Cancer. 2025;25(5):324-340 - PMID: 39972158 - DOI: 10.1038/s41568-025-00796-w
Lymph nodes link sex-biased immune aging to compromised antigen recognition.
Single-nuclear transcriptomics of lymphedema-associated adipose reveals a pro-lymphangiogenic stromal cell population.
Exercise-Induced Cardiac Lymphatic Remodeling Mitigates Inflammation in the Aging Heart.
Aging Cell. 2025;:e70043 - PMID: 40083143 - DOI: 10.1111/acel.70043
Inhibiting B-cell-mediated Immunosuppression to Enhance the Immunotherapy Efficacy in Hepatocellular Carcinoma.
S2303: phase II/III trial of paclitaxel + ramucirumab +/- nivolumab in gastric and esophageal adenocarcinoma (PARAMUNE)
Future Oncol. 2025;21(11):1325-1331 - PMID: 40155326 - PMCID: PMC12051544 - DOI: 10.1080/14796694.2025.2485020
A prospective study of immune responses in patients with lung metastases treated with stereotactic body radiotherapy with or without concurrent systemic treatment.
Radiother Oncol. 2025;207:110889 - PMID: 40209858 - DOI: 10.1016/j.radonc.2025.110889
Inhibiting B-cell-mediated Immunosuppression to Enhance the Immunotherapy Efficacy in Hepatocellular Carcinoma.
IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against pancreatic cancer in mice with obesity.
J Immunother Cancer. 2025;13(5):ePub - PMID: 40413022 - PMCID: PMC12104899 - DOI: 10.1136/jitc-2024-011404
The cellular dance that splits vessels.
Proc Natl Acad Sci U S A. 2025;122(22):e2508260122 - PMID: 40424133 - DOI: 10.1073/pnas.2508260122
Effect of bevacizumab on non-target intracranial meningiomas and non-vestibular schwannomas in NF2-related schwannomatosis: NF104.
J Neurooncol. 2025;:ePub - PMID: 40434540 - DOI: 10.1007/s11060-025-05020-1
Mathematical Modeling and Association Analysis Deciphers the Impact of the Gut Microbiome on Cancer Immunotherapy.
Cancer Res. 2025;:ePub - PMID: 40439571 - DOI: 10.1158/0008-5472.CAN-24-2232
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